Molecular regulation of luteal progesterone synthesis in domestic ruminants

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Molecular regulation of progesterone synthesis in the bovine corpus luteum

In bovine luteal cells, progesterone can directly affect its own synthesis by increasing the activity of 3β-HSD. The effect of progesterone on its own secretion coincides with increased expression of the genes for 3βHSD, StAR, and cytochrome P450scc. Therefore, progesterone regulates its own synthesis by affecting the activity of the enzymes that take part in luteal steroidogenesis, and also by...

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p LASMA concentrations of progesterone in the ewe reach a plateau by about the 10th day of the estrous cycle, though there is considerable variation between days and animals (Stabenfeldt, Holt and Ewing, 1969; Thorburn, Bassett and Smith, 1969). Thorburn et al. (1969) observed variation in the luteal phase peak values of progesterone in the same ewes in successive cycles, which they speculated ...

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Board-invited review: Estrogen and progesterone signaling: genomic and nongenomic actions in domestic ruminants.

Progesterone and estrogens play key roles in regulating various physiological phenomena related to normal growth, development, and reproduction of domestic animals. This review focuses on the mechanisms by which progesterone and estrogens regulate the reproductive processes in these animals. The majority of research on the actions of progesterone and estrogens on the reproductive systems of cat...

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ژورنال

عنوان ژورنال: Bioscientifica Proceedings

سال: 2019

ISSN: 2515-0227

DOI: 10.1530/biosciprocs.4.015